ITPI
Intrauterine Tuboperitoneal Insemination (ITPI)
An advanced insemination technique delivering sperm to both the uterus and fallopian tubes simultaneously.
What is Intrauterine Tuboperitoneal Insemination (ITPI)?
Intrauterine Tuboperitoneal Insemination (ITPI) is an enhanced insemination technique in which a larger volume of prepared sperm suspension (typically 4\u20138 mL) is injected into the uterine cavity under gentle pressure, causing the sperm to flow through the fallopian tubes and into the peritoneal cavity. This approach maximises sperm distribution throughout the female reproductive tract and has shown higher pregnancy rates than standard IUI in selected patient groups. ITPI is performed at Ova IVF by experienced specialists using a specially designed catheter and balloon system.
Who is this for?
- Couples with unexplained infertility who have not conceived with standard IUI
- Women with mild endometriosis
- Couples with mild to moderate male factor infertility
- Women with patent (open) fallopian tubes confirmed by HSG or laparoscopy
- Couples seeking a more effective alternative to IUI before IVF
- Women with cervical factor infertility
Key Benefits
Step-by-Step Procedure
A clear, transparent walkthrough of every stage of your ITPI treatment at Ova IVF.
Baseline Assessment & Tubal Patency Confirmation
Hysterosalpingography (HSG) or laparoscopy confirms that both fallopian tubes are patent (open) before ITPI is performed, as tubal patency is essential for the procedure.
Ovarian Stimulation & Monitoring
Mild ovarian stimulation with oral agents or low-dose gonadotropins is used to develop 1–2 dominant follicles. Serial ultrasound monitoring tracks follicle growth.
Trigger Injection
A trigger injection is administered when the dominant follicle reaches 18–20mm to time ovulation precisely. ITPI is scheduled 36–40 hours later.
Semen Sample Preparation
A semen sample is collected and processed in the laboratory. A larger volume of prepared sperm suspension (4–8 mL) is prepared compared to standard IUI.
Catheter Placement & Balloon Occlusion
A specially designed catheter with an inflatable balloon is gently inserted through the cervix into the uterine cavity. The balloon is inflated to occlude the cervical canal and prevent backflow.
Sperm Injection
The prepared sperm suspension is slowly injected under gentle pressure. The larger volume causes sperm to flow through the uterine cavity, into the fallopian tubes, and into the peritoneal cavity, maximising sperm distribution.
Post-Procedure Care
The balloon is deflated and the catheter removed. You rest for 15–20 minutes. Mild cramping may occur. Progesterone luteal support is prescribed.
Pregnancy Test
A blood beta-hCG test is performed 14 days after ITPI to confirm pregnancy.
Frequently Asked Questions
How is ITPI different from IUI?
IUI places a small volume (0.5–1 mL) of sperm directly into the uterine cavity. ITPI uses a larger volume (4–8 mL) injected under gentle pressure, causing sperm to travel through the tubes into the peritoneal cavity, increasing the chance of sperm meeting the egg.
Is ITPI painful?
Most women experience mild uterine cramping during and after the procedure, similar to period pain. The procedure is performed without anaesthesia and takes approximately 10–15 minutes.
Do I need open fallopian tubes for ITPI?
Yes. Patent fallopian tubes are essential for ITPI. Tubal patency must be confirmed by HSG or laparoscopy before the procedure is performed.
Ready to Begin Your ITPI Journey?
Our specialists are here to guide you. Call us or book a consultation today.